SPECTRUM CHEMICAL MFG CORP -- SULFANILAMIDE  -- 6505-00N082127
<pre>=====================  Product Identification  =====================

Product ID:SULFANILAMIDE
MSDS Date:02/21/1991
FSC:6505
NIIN:00N082127
=== Responsible Party ===
Company Name:SPECTRUM CHEMICAL MFG CORP
Address:14422 SOUTH SAN PEDRO ST
City:GARDENA
State:CA
ZIP:90248
Country:US
Info Phone Num:310-516-8000
Emergency Phone Num:310-516-8000;800-414-9300(CHEMTREC)
CAGE:63415
=== Contractor Identification ===
Company Name:SPECTRUM LABORATORY PRODUCTS INC
Address:14422 S SAN PEDRO ST
Box:City:GARDENA
State:CA
ZIP:90248-2027
Country:US
Phone:310-516-8000/FAX: 310-516-9843
CAGE:63415

=============  Composition/Information on Ingredients  =============

Ingred Name:SULFANILAMIDE
CAS:63-74-1
RTECS #:WO8400000
Fraction by Wt: 100%
OSHA PEL:N/K 
ACGIH TLV:N/K 

Ingred Name:SUPDAT: EXPOS MAY OCCUR. EFTS ON NEWBORNS REPORTED FROM
    ORAL ADMIN FOR 1-22 DAYS IN PREGNANT RATS. TOXICITY:POIS (ING 3)
RTECS #:9999999ZZ

Ingred Name:ING 2:MAY AFFECT LIVER & KIDNEYS. CONCURRENT ADMIN OF
    VARIOUS DRUGS W/SULFANILAMIDE MAY CAUSE ADVERSE EFTS. ORAL/(ING 4)
RTECS #:9999999ZZ

Ingred Name:ING 3:TOPICAL USE OF PARA-AMINOBENZOIC ACID ANTAGONIZED
    SULFONAMIDE EFT; MARKEDLY INCRD ANTICOAGULANT EFTS W/ORAL(ING 5)
RTECS #:9999999ZZ

Ingred Name:ING 4: ANTICOAGULANTS; POSS ADDITIVE BONE MARROW DEPRESS
    W/CHLORAPHENICOL; POSS INCRD HYPOGLYCEMIA EFTS W/ORAL (ING 6)
RTECS #:9999999ZZ

Ingred Name:ING 5: HYPOGLYCEMICS; POSS ADDITIVE HEPATOTOXICITY
    W/HEPATOTOXINS; ACIDIFIES URINE, INCREASING POSSIBILITY OF (ING 7)
RTECS #:9999999ZZ

Ingred Name:ING 6: SULFONAMIDE CRYSTALLURIA W/METHENAMINE; INCR IN
    SERUM METHOTREXATE LEVELS, POSS LEADING TO TOXICITY WITH (ING 8)
RTECS #:9999999ZZ

Ingred Name:ING 7: METHOTREXATE; MAY INCR HEPATIC METABOLISM OR DECR
    ABSORPTION OF ESTROGEN W/ORAL CONTRACEPTIVES; INCRD (ING 9)
RTECS #:9999999ZZ

Ingred Name:ING 8: PHENYTOIN EFT, POSS LEADING TO TOXICITY W/PHENYTOIN
    & OTHER HYDANTOINS; INCRD THIOPENTAL LEVELS, POSS (ING 10)
RTECS #:9999999ZZ

Ingred Name:ING 9: LEADING TO TOXICITY W/THIOPENTAL.
RTECS #:9999999ZZ

Ingred Name:FIRST AID PROC:UPPER & LOWER LIDS, UNTIL NO EVID OF CHEM
    REMAINS (AT LST 15-20 MIN). GET MED ATTN IMMED. INGEST:(ING 12)
RTECS #:9999999ZZ

Ingred Name:ING 11: REMOVE FROM EXPOS AREA. IF LG DOSE SWALLOWED, GIVE
    EMETIC OR PERFORM GASTRIC LAVAGE. TO INCR RENAL (ING 13)
RTECS #:9999999ZZ

Ingred Name:ING 12: EXCRETION, URINE SHOULD BE ALKINIZED BY ORAL OR IV
    SODIUM BICARBONATE. TREATMENT SHOULD BE BY QUALIFIED (ING 14)
RTECS #:9999999ZZ

Ingred Name:ING 13: MED PERS. GET MED ATTN IMMED. FOLLOWING ANTIDOTE
    RECOMD, HOWEVER, DECISION TO ADMIN & ACTUAL DOSE REQD (ING 15)
RTECS #:9999999ZZ

Ingred Name:ING 14: SHOULD BE MADE BY QUALIFIED MED PERS. WHEN
    METHEMOGLOBIN CONC IS >25-40% OR IN PRESENCE OF SYMPS GIVE (ING 16)
RTECS #:9999999ZZ

Ingred Name:ING 15: METHYLENE BLUE, 1% SOLN, 0.1 ML/KG IV OVER 10-MIN.
    CYANOSIS MAY DISAPPEAR W/IN MINS/PERSIST DEPENDING ON(ING 17)
RTECS #:9999999ZZ

Ingred Name:ING 16: DEGREE OF METHEMOGLOBINEMIA. THERAPEUTIC DOSES OF
    METHYLENE BLUE ADMIN IV MAY CAUSE RISE IN BLOOD PRESS,(ING 18)
RTECS #:9999999ZZ

Ingred Name:ING 17: NAUS & DIZZ. LARGER DOSES (>500MG) CAUSE VOMIT,
    DIARR, CHEST PAIN, MENTAL CONFUSN, CYANOSIS & SWEAT. (ING 19)
RTECS #:9999999ZZ

Ingred Name:ING 18:HEMOLYTIC ANEMIA OCCURRED SEVERAL DAYS AFTER ADMIN;
    EFTS TEMPORARY & NO RPTS OF FATALITIES. IF METHYLENE (ING 20)
RTECS #:9999999ZZ

Ingred Name:ING 19: BLUE IS NOT AVAIL, GIVE ASCORBIC ACID, 1G SLOWLY
    IV. W/OUT TREATMENT, METHEMOGLOBINEMIA LEVELS OF 20- (ING 21)
RTECS #:9999999ZZ

Ingred Name:ING 20: 30% REVERT BACK TO NORM W/IN 3 DAYS. ANTIDOTE
    SHOULD BE ADMIN BY QUALIFIED MED PERSONNEL.
RTECS #:9999999ZZ

Ingred Name:RESP PROT: FULL FACEPIECE RESP W/HIGH-EFFICIENCY
    PARTICULATE FILTER. ANY POWERED AIR-PURIFYING RESP W/TIGHT- (ING
    23)
RTECS #:9999999ZZ

Ingred Name:ING 22: FITTING FACEPIECE & HIGH-EFFICIENCY PARTICULATE
    FILTER. ANY TYPE 'C' SUPPLIED-AIR RESP W/FULL FACEPIECE (ING 24)
RTECS #:9999999ZZ

Ingred Name:ING 23:OPERATED IN PRESS-DEMAND/OTHER POS PRESS MODE OR
    W/FULL FACEPIECE HELMET/HOOD OPERATED IN CONTINUOUS-FLOW(ING 25)
RTECS #:9999999ZZ

Ingred Name:ING 24: MODE. ANY SCBA W/FULL FACEPIECE OPERATED IN
    PRESS-DEMAND OR OTHER POSITIVE PRESS MODE.
RTECS #:9999999ZZ

=====================  Hazards Identification  =====================

LD50 LC50 Mixture:LD50: (ORAL, RAT) 10,500 MG/KG
Routes of Entry: Inhalation:YES  Skin:YES  Ingestion:YES
Reports of Carcinogenicity:NTP:NO    IARC:NO	OSHA:NO
Health Hazards Acute and Chronic:ACUTE: INHAL: NO DATA AVAIL. SKIN: NO
    LOCAL EFTS REPORTED. SYSTEMIC EFTS FROM ORAL ADMIN MAY INCL
    MACULOPAPULAR ERYTHEMATOUS SKIN ERUPTIONS, BULBOUS LESIONS OF SKIN
    & SENSITIVITY RXNS. EYES: NO LOCAL	EFTS REPORTED. SYSTEMIC EFTS
    FROM ORAL ADMIN MAY INCL ACUTE TRANSIENT MYOPIA, SOMETIMES
    ACCOMPANIED BY (EFTS OF OVEREXP)
Explanation of Carcinogenicity:NOT RELEVANT
Effects of Overexposure:HLTH HAZ: ASTIGMATISM, CONJ & TEMPORARY
    IMPAIRMENT OF DEPTH PERCEPTION. INGEST:MAY CAUSE METHEMOGLOBINEMIA
    W/CYANOSIS. OTHER SYMPS MAY INCL CEREBRAL & GI EFTS SUCH AS
    ANOREXIA, COLIC, NAUSEA, VOMIT, D IZZ, HDCH, DROW/EVEN UNCON. TOX
    FEVER MAY DEVELOP ONE/MORE DAYS AFTER INFECTIOUS FEVER HAS SUBSIDED
    & PRECEDES (SUPDAT)
Medical Cond Aggravated by Exposure:NONE SPECIFIED BY MANUFACTURER.

=======================  First Aid Measures  =======================

First Aid:INHAL: REMOVE TO FRESH AIR IMMED. IF BRTHG STOPS, PERFORM
    ARTF RESP. KEEP WARM & AT REST. TREAT SYMP & SUPPORTIVELY. GET MED
    ATTN IMMED. SKIN: REMOVE CONTAMD CLTHG & SHOES IMMED. WASH AFFECTED
    AREA W/ SOAP OR MILD DETERGENT & LARGE AMTS OF WATER UNTIL NO EVID
    OF CHEM REMAINS (APPROX 15-20 MIN). GET MED ATTN IMMED. EYES: WASH
    IMMED W/LARGE AMTS OF WATER OR NORMAL SALINE, OCCASNLY LIFTING (ING
    11)

=====================  Fire Fighting Measures  =====================

Flash Point:NONFLAMMABLE
Extinguishing Media:DRY CHEMICAL, CARBON DIOXIDE, WATER SPRAY OR
    REGULAR FOAM. FOR LARGER FIRES, USE WATER SPRAY, FOG OR REGULAR
    FOAM.
Fire Fighting Procedures:USE NIOSH APPRVD SCBA & FULL PROTECTIVE
    EQUIPMENT . NO ACUTE HAZARD. MOVE CNTNR FROM FIRE AREA IF POSSIBLE.
    AVOID BREATHING VAPORS OR DUSTS; KEEP UPWIND.
Unusual Fire/Explosion Hazard:NEGLIGIBLE FIRE HAZARD WHEN EXPOSED TO
    HEAT OR FLAME.

==================  Accidental Release Measures  ==================

Spill Release Procedures:DO NOT TOUCH SPILL. STOP LEAK IF W/OUT RISK.
    SM SPILL:TAKE UP W/SAND OR OTHER ABSORB & PLACE INTO CNTNRS. LG
    SPILL:DIKE FAR AHEAD OF SPILL FOR LATER DISP. KEEP UNNEC PEOPLE
    AWAY. ISOLATE HAZ AREA & DE NY ENTRY. VENT CLSD SPACES BEFORE
    ENTERING.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

======================	Handling and Storage  ======================

Handling and Storage Precautions:MAY BURN BUT DOES NOT IGNITE READILY.
    AVOID CONTACT WITH STRONG OXIDIZERS, EXCESSIVE HEAT, SPARKS OR OPEN
    FLAME.
Other Precautions:NONE SPECIFIED BY MANUFACTURER.

=============  Exposure Controls/Personal Protection  =============

Respiratory Protection:FOLLOWING RESPS RECOMD. SPECIFIC RESP SELECTED
    MUST BE BASED ON CONTAM LEVELS IN WORKPLACE, SPECIFIC OPERATION,
    MUST NOT EXCEED WORKING LIMS OF RESP & MUST BE NIOSH APPRVD. ANY
    DUST & MIST RESP W/FULL  FACEPIECE. ANY AIR-PURIFYING (ING 22)
Ventilation:PROVIDE LOCAL EXHAUST OR GENERAL DILUTION VENTILATION
    SYSTEM.
Protective Gloves:IMPERVIOUS GLOVES .
Eye Protection:ANSI APPRVD CHEM WORKERS GOGGLES .
Other Protective Equipment:ANSI APPRVD EYE WASH & DELUGE SHOWER . WEAR
    APPROP PROT (IMPERVIOUS) CLTHG & EQUIP TO PVNT RPTD/PRLNGD SKIN
    CNTCT.
Work Hygienic Practices:NONE SPECIFIED BY MANUFACTURER.
Supplemental Safety and Health
PH: 5.8-6.1 @ 0.5% SOLN. EFTS OF OVEREXP: DEVELOPMENT OF MORE SERIOUS
    MANIFESTATIONS OF POISONING, NAMELY ACIDOSIS, DIURESIS, ACUTE
    HEMOLYTIC ANEMIA, AGRANULOCYTIC ANGINA, DERM OR TOXIC NEURITIS.
    JAUN  OF HEPATIC ORIGIN OCCASNLY OCCURS. CHRONIC:
    INHAL/SKIN/EYES:NO DATA AVAIL. INGEST:SYMPS SIMILAR TO ACUTE (ING
    2)

==================  Physical/Chemical Properties  ==================

Melt/Freeze Pt:M.P/F.P Text:329F,165C
Spec Gravity:1.08
pH:SUPDAT
Solubility in Water:7%
Appearance and Odor:WHITE TO YELLOW POWDER.

=================  Stability and Reactivity Data  =================

Stability Indicator/Materials to Avoid:YES
NO DATA AVAILABLE.
Stability Condition to Avoid:STABLE UNDER NORMAL TEMPERATURES AND
    PRESSURES.
Hazardous Decomposition Products:THERMAL DECOMPOSITION PRODUCTS INCLUDE
    TOXIC OXIDES OF NITROGEN AND SULFUR.

====================  Disposal Considerations  ====================

Waste Disposal Methods:DISPOSAL MUST BE IN ACCORDANCE WITH FEDERAL,
    STATE AND LOCAL REGULATIONS .

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